milad amini masouleh; Gholamreza Chalabianloo; reza abdi
Abstract
Introduction: Working memory deficit is one of the most common complaints in post-stroke patients. The present study aimed to investigate the efficacy of the con-commitment use of unihemispheric concurrent dual-site a-tDCS (a-tDCSUHCDS), computer-assisted cognitive rehabilitation and conventional (Single ...
Read More
Introduction: Working memory deficit is one of the most common complaints in post-stroke patients. The present study aimed to investigate the efficacy of the con-commitment use of unihemispheric concurrent dual-site a-tDCS (a-tDCSUHCDS), computer-assisted cognitive rehabilitation and conventional (Single site) a-tDCS in comparison with computer-assisted cognitive rehabilitation without tDCS on the working memory in stroke patients. Method:32 participants (21 males and11 females; age range 40-65years) with subacute stroke were selected by purposeful sampling method & randomly assigned to three experimental conditions and a controlled group with sham stimulation. All groups completed sessions of the Dual N-back training task. A-tDCSUHCDS group received anodal tDCS over the left DLPFC and M1 and conventional (Single site) a-tDCS group received anodal tDCS over the left DLPFC. Result: A repeated measures analysis of variance revealed that the a-tDCSUHCDS group had the larger improvement in working memory tasks after the intervention. Also, at the 8-weeks follow-up, the a-tDCSUHCDS group still had larger improvements in mentioned tasks. Conclusion: These results indicated that there may be potential for the concomitant use of a-tDCSUHCDS and computer-assisted cognitive rehabilitation by increasing the excitability of the cortical network of brain regions that play an important role in executive functions, to enhance the efficiency of the cognitive rehabilitation programs of the stroke patients.
Gholamreza Chalabianloo; mahsa meghrazi; Zahra Keshtgar
Abstract
Aim: Schizophrenia is one of the most prevalent severe psychiatric disorders that including variety of cognitive, emotional & behavioral symptoms in which formal thought problem is one of the determinant factors of prognosis. The aim of the study was comparison of cortical activities in schizophrenic ...
Read More
Aim: Schizophrenia is one of the most prevalent severe psychiatric disorders that including variety of cognitive, emotional & behavioral symptoms in which formal thought problem is one of the determinant factors of prognosis. The aim of the study was comparison of cortical activities in schizophrenic patients with & without formal thought. Method: 60 schizophrenic patients(31 patients with formal thought disorder & 29 patients without formal thought disorder) were selected by goal oriented sampling procedure based on including & excluding criteria. Cortical activities of all participants recorded by 19 channels EEG. Findings: Data showed to schizophrenics without formal thought disorders, the absolute power of delta & beta bands were lower & theta band was higher in patients with formal thought disorder in anterior regions. Also, patients with formal thought disorder revealed decreased absolute power in delta, alpha & beta bands in posterior regions. Conclusion: Our results are in favor of hypofrontality hypothesis of schizophrenia & indicated that patients with formal thought disorder, had cortical hypo arousal that result in severe cognitive problems.
Gholamreza Chalabianloo; Zahra Keshtgar; Forough Farrokhzad
Abstract
Aim: Major depressive disorder is a prevalent psychiatric disorder in which an emotional processing problem is one of the main characteristics of the disorder. Research demonstrates the role of cortical electrical activity components in emotional processing in depression disorder. So the aim of the study ...
Read More
Aim: Major depressive disorder is a prevalent psychiatric disorder in which an emotional processing problem is one of the main characteristics of the disorder. Research demonstrates the role of cortical electrical activity components in emotional processing in depression disorder. So the aim of the study is to determine the role of cortical coherence in predicting emotional processing in patients with major depressive disorder. Method: 60 patients with major depressive mood disorder selected based on DSM-5. Cortical electrical activities of patients recorded by 21 channels EEG & coherence of different bands for anterior, central & posterior regions in two hemispheres calculated by neuro guide software. Emotion processing evaluated by Williams et al (2008) emotional faces detection task. Findings: Regression analysis indicated that coherence of alpha in anterior, beta in central regions of the left hemisphere, and alpha in anterior & beta in posterior regions in right hemisphere predicted positive emotion processing. Also, Coherence of theta & alpha bands in anterior regions in the left hemisphere positively, and left central & right posterior beta bands negatively predicted negative emotion processing. Conclusion: The coherence of theta, alpha & beta bands in anterior & posterior regions play a key role in predicting emotional processing in depressive patients. The results indicated that the anterior regions detect the type of emotion & posterior regions detect arousal severity.
